Differential Regulation of Cathepsin S and Cathepsin L in Interferon γ–treated Macrophages
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چکیده
منابع مشابه
Differential Regulation of Cathepsin S and Cathepsin L in Interferon γ–treated Macrophages
Cathepsin S (catS) and cathepsin L (catL) mediate late stages of invariant chain (Ii) degradation in discrete antigen-presenting cell types. Macrophages (Mphis) are unique in that they express both proteases and here we sought to determine the relative contribution of each enzyme. We observe that catL plays no significant role in Ii cleavage in interferon (IFN)-gamma-stimulated Mphis. In additi...
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ژورنال
عنوان ژورنال: Journal of Experimental Medicine
سال: 2003
ISSN: 1540-9538,0022-1007
DOI: 10.1084/jem.20020978